In vitro biocompatibility of diazirine-grafted biomaterials

• Main Authors: Djordjevic, Ivan, Wicaksono, Gautama, Solic, Ivan, Steele, Terry W. J.
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Materials::Biomaterials; Engineering::Bioengineering; Diazirine; Genotoxicity
• Online Access: https://hdl.handle.net/10356/144482
• Institution: Nanyang Technological University

Photoactivation of aryl-diazirines is an emerging method of rapid, covalent crosslinking under ambient conditions. These attributes make those compounds candidates for grafting onto inert polymer backbones in order to produce stimuli-sensitive biomaterials. However, no risk assessments are available...