Enterococcus faecalis adapts to antimicrobial conjugated oligoelectrolytes by lipid rearrangement and differential expression of membrane stress response genes

• المؤلفون الرئيسيون: Chilambi, Gayatri Shankar, Hinks, Jamie, Matysik, Artur, Zhu, Xinyi, Choo, Pei Yi, Liu, Xianghui, Chan-Park, Mary B., Bazan, Guillermo C., Kline, Kimberly A., Rice, Scott A.
• مؤلفون آخرون: Interdisciplinary Graduate School (IGS)
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Biological sciences; Enterococcus Faecalis; Conjugated Oligolectrolytes
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/145240
• المؤسسة: Nanyang Technological University

Conjugated oligoelectrolytes (COEs) are emerging antimicrobials with broad spectrum activity against Gram positive and Gram negative bacteria as well as fungi. Our previous in vitro evolution studies using Enterococcus faecalis grown in the presence of two related COEs (COE1-3C and COE1-3Py) led to...