Acquisition of plasmid with carbapenem-resistance gene blaKPC2 in hypervirulent Klebsiella pneumoniae, Singapore

• Main Authors: Chen, Yahua, Marimuthu, Kalisvar, Teo, Jeanette, Venkatachalam, Indumathi, Cherng, Benjamin Pei Zhi, Wang, Liang De, Prakki, Sai Rama Sridatta, Xu, Weizhen, Tan, Yi Han, Nguyen, Lan Chi, Koh, Tse Hsien, Ng, Oon Tek, Gan, Yunn-Hwen
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Medicine; Enterobacteriaceae; K1
• Online Access: https://hdl.handle.net/10356/145330
• Institution: Nanyang Technological University

The convergence of carbapenem-resistance and hypervirulence genes in Klebsiella pneumoniae has led to the emergence of highly drug-resistant superbugs capable of causing invasive disease. We analyzed 556 carbapenem-resistant K. pneumoniae isolates from patients in Singapore hospitals during 2010-201...