DL-CRISPR : a deep learning method for off-target activity prediction in CRISPR/Cas9 with data augmentation
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR- associated (Cas) system is a popular and easy to use gene-editing technique, but it has off-target risk. Cutting the off-target sites will harm the cells severely, hence in silico methods are needed to help to avoid this. Mos...
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Main Authors: | Zhang, Yu, Long, Yahui, Yin, Rui, Kwoh, Chee Keong |
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Other Authors: | School of Computer Science and Engineering |
Format: | Article |
Language: | English |
Published: |
2021
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/145675 |
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Institution: | Nanyang Technological University |
Language: | English |
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