Carbene-catalyzed reaction of indolyl methylenemalononitriles and enals for access to complex tetrahydrocarbazoles

A carbene-catalyzed enantioselective cascade reaction of substituted methylenemalononitriles and α-bromoenals is disclosed. Key steps of this cascade process include a formal [4 + 2] cycloaddition, aldol reaction, and intramolecular lactonization. Our reaction offers streamlined and highly stereosel...

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Main Authors: Mou, Chengli, Zhou, Liejin, Song, Runjiang, Chai, Huifang, Hao, Lin, Chi, Robin Yonggui
其他作者: School of Physical and Mathematical Sciences
格式: Article
語言:English
出版: 2021
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在線閱讀:https://hdl.handle.net/10356/148641
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