Carbene-Catalyzed Dynamic Kinetic Resolution of Carboxylic Esters

• Main Authors: Chen, Xingkuan, Fong, Jacqueline Zi Mei, Xu, Jianfeng, Mou, Chengli, Lu, Yunpeng, Yang, Song, Song, Bao-An, Chi, Yonggui Robin
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2017
• Subjects: Carbene-catalyzed reactions; Carboxylic esters
• Online Access: https://hdl.handle.net/10356/82225; http://hdl.handle.net/10220/43496
• Institution: Nanyang Technological University

Carbene-catalyzed reaction of carboxylic esters has the potential to offer effective synthetic solutions that cannot be readily achieved by using the more conventional aldehyde-type substrates. Here we report the first carbene-catalyzed dynamic kinetic resolution of α,α-disubstituted carboxylic este...