Cyclin D1 integrates G9a-mediated histone methylation

• Main Authors: Li, Zhiping, Jiao, Xuanmao, Di Sante, Gabriele, Ertel, Adam, Casimiro, Mathew C., Wang, Min, Katiyar, Sanjay, Ju, Xiaoming, Klopfenstein, D. V., Tozeren, Aydin, Dampier, William, Chepelev, Iouri, Jeltsch, Albert, Pestell, Richard George
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Medicine; Breast Cancer; Checkpoint Signalling
• Online Access: https://hdl.handle.net/10356/148670
• Institution: Nanyang Technological University

Lysine methylation of histones and non-histone substrates by the SET domain containing protein lysine methyltransferase (KMT) G9a/EHMT2 governs transcription contributing to apoptosis, aberrant cell growth, and pluripotency. The positioning of chromosomes within the nuclear three-dimensional space i...