Features and functional importance of key residues of the Mycobacterium tuberculosis cytochrome bd oxidase

• Main Authors: Sviriaeva, Ekaterina, Manimekalai, Malathy Sony Subramanian, Grüber, Gerhard, Pethe, Kevin
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Biological sciences::Biochemistry; Bioenergetics; Respiration
• Online Access: https://hdl.handle.net/10356/149230
• Institution: Nanyang Technological University

Cytochrome bd (cyt-bd) oxygen reductases have a high affinity to oxygen and use the two electrons provided by ubiquinol or menaquinol, like in mycobacteria, to reduce oxygen to water. Although they do not pump protons from the cytoplasmic to the periplasmic side, they generate a proton motive fo...