Incorporating G-C pair-recognizing Guanidinium into PNAs for sequence and structure specific recognition of dsRNAs over dsDNAs and ssRNAs

Incorporating G-C pair-recognizing Guanidinium into PNAs for sequence and structure specific recognition of dsRNAs over dsDNAs and ssRNAs

Recognition of RNAs under physiological conditions is important for the development of chemical probes and therapeutic ligands. Nucleobase-modified dsRNA-binding PNAs (dbPNAs) are promising for the recognition of dsRNAs in a sequence and structure specific manner under near-physiological conditions....

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Bibliographic Details
Main Authors: Krishna, Manchugondanahalli S., Wang, Zhenzhang, Zheng, Liangzhen, Bowry, Jogesh, Ong, Alan Ann Lerk, Mu, Yuguang, Prabakaran, Mookkan, Chen, Gang
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2021
Subjects:
Science::Biological sciences
Guanidinium
Double-stranded RNAs
Online Access:https://hdl.handle.net/10356/150414
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/150414

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