Binding of dsRNAs by PNAs containing Q, modified Q and 2-thio Uracil monomers
Peptide nucleic acids (PNAs) have been developed as chemical probes and therapeutic ligands in RNA duplex recognition. PNAs bind to ribonucleic acid (RNA) duplexes via complementary Hoogsteen hydrogen bonding to form PNA·RNA2 triplexes. In this study, modifications were made to chemically synthesize...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2019
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| Online Access: | http://hdl.handle.net/10356/79017 |
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| Institution: | Nanyang Technological University |
| Language: | English |