A new method for the construction of coarse-grained models of large biomolecules from low-resolution cryo-electron microscopy data

The rapid development of cryo-electron microscopy (cryo-EM) has led to the generation of significant low-resolution electron density data of biomolecules. However, the atomistic details of huge biomolecules usually cannot be obtained because it is very difficult to construct all-atom models for MD s...

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Bibliographic Details
Main Authors: Zhang, Yuwei, Xia, Kelin, Cao, Zexing, Gräter, Frauke, Xia, Fei
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/150624
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Institution: Nanyang Technological University
Language: English