Time-resolved observations of liquid − liquid phase separation at the nanoscale using in situ liquid transmission electron microscopy

• Main Authors: Le Ferrand, Hortense, Duchamp, Martial, Gabryelczyk, Bartosz, Cai, Hao, Miserez, Ali
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Engineering::Materials; Protein; Nucleation
• Online Access: https://hdl.handle.net/10356/150950
• Institution: Nanyang Technological University

Liquid–liquid phase separation (LLPS) of proteins into concentrated microdroplets (also called coacervation) is a phenomenon that is increasingly recognized to occur in many biological processes, both inside and outside the cell. While it has been established that LLPS can be described as a spinodal...