Biophysical and structural characterization of nucleic acids: I. Structure, ions and folding/unfolding kinetics of left-handed G-quadruplexes II. Interaction of ligands with G-quadruplexes III. Characterization of nucleic acids on surface towards development of biosensors
G-quadruplexes are non-canonical structures of nucleic acid which has gained huge interest in the last few decades due to its crucial role in various biological processes, and for its applications as robust synthetic polymer in the field of therapeutics and nanotechnology. G-quadruplex structures ar...
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格式: | Thesis-Doctor of Philosophy |
語言: | English |
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Nanyang Technological University
2021
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在線閱讀: | https://hdl.handle.net/10356/151308 |
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機構: | Nanyang Technological University |
語言: | English |