Trimerization of the N-terminal tail of Zika virus NS4A protein : a potential in vitro antiviral screening assay

• المؤلفون الرئيسيون: To, Janet, Torres, Jaume
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2021
• الموضوعات: Science::Biological sciences; Zika Virus; NS4A
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/151879
• المؤسسة: Nanyang Technological University

The nonstructural (NS) protein NS4A in flaviviruses is a membrane protein that is critical for virulence, and, among other roles, it participates in membrane morphogenesis. In dengue virus (DENV), the NS4A hydrophilic N–terminal tail, together with the first transmembrane domain, is involved in both...