IRE-1 regulates cellular homeostasis during disrupted lipid metabolism

• المؤلف الرئيسي: Koh, Jhee Hong
• مؤلفون آخرون: Guillaume Thibault
• التنسيق: Thesis-Doctor of Philosophy
• اللغة: English
• منشور في: Nanyang Technological University 2021
• الموضوعات: Science::Biological sciences::Molecular biology
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/152743
• المؤسسة: Nanyang Technological University

Metabolic disorders, such as non-alcoholic fatty liver disease (NAFLD), are emerging as epidemics that affect the global population. One facet of these disorders is attributed to the disturbance of membrane lipid composition. Typically activated by misfolded protein accumulation within the ER, pertu...