Conformational states of Zika virus non-structural protein 3 determined by molecular dynamics simulations with small-angle X-Ray scattering data

• المؤلفون الرئيسيون: Zhu, Guanhua, Pan, Ankita, Grüber, Gerhard, Lu, Lanyuan
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2021
• الموضوعات: Science::Biological sciences; Zika Virus; Non-structural Protein 3
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/152748
• المؤسسة: Nanyang Technological University

Zika virus (ZIKV) has become a great public health emergency. Its non-structural protein 3 (NS3) is a key enzyme in viral replication and has been considered as a potential therapeutic target. A conformational characterization of ZIKV NS3 is critical for a comprehensive understanding of its molecula...