Effects of lipid environment on aquaporin : exploration of styrene-maleic acid nanodiscs for single-particle cryo-EM structural determination
Aquaporin Z (AqpZ) is a water channel protein native to Escherichia coli with lipid-dependent activity. However, AqpZ structural changes that may explain water flux changes have not yet been elucidated. Thus, my aim was to use styrene-maleic acid copolymers (SMAc) to produce AqpZ-nanodiscs suitable...
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| Format: | Final Year Project |
| Language: | English |
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Nanyang Technological University
2021
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| Online Access: | https://hdl.handle.net/10356/153267 |
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| Institution: | Nanyang Technological University |
| Language: | English |