Tracking oxidation-induced alterations in fibrin clot formation by NMR-based methods

Plasma fibrinogen is an important coagulation factor and susceptible to post-translational modification by oxidants. We have reported impairment of fibrin polymerization after exposure to hypochlorous acid (HOCl) and increased methionine oxidation of fibrinogen in severely injured trauma patients. M...

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Bibliographic Details
Main Authors: Lau, Wai-Hoe, White, Nathan J., Yeo, Tsin Wen, Gruen, Russell L., Pervushin, Konstantin
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/153773
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Institution: Nanyang Technological University
Language: English