Tracking oxidation-induced alterations in fibrin clot formation by NMR-based methods
Plasma fibrinogen is an important coagulation factor and susceptible to post-translational modification by oxidants. We have reported impairment of fibrin polymerization after exposure to hypochlorous acid (HOCl) and increased methionine oxidation of fibrinogen in severely injured trauma patients. M...
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Main Authors: | Lau, Wai-Hoe, White, Nathan J., Yeo, Tsin Wen, Gruen, Russell L., Pervushin, Konstantin |
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Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Article |
Language: | English |
Published: |
2021
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/153773 |
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Institution: | Nanyang Technological University |
Language: | English |
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