Amide-directed C-H sodiation by a sodium hydride/iodide composite

A new protocol for amide-directed ortho and lateral C-H sodiation is enabled by sodium hydride (NaH) in the presence of either sodium iodide (NaI) or lithium iodide (LiI). The transient organosodium intermediates could be transformed into functionalized aromatic compounds.

Saved in:

Bibliographic Details
Main Authors:	Huang, Yinhua, Chan, Guo Hao, Chiba, Shunsuke
Other Authors:	School of Physical and Mathematical Sciences
Format:	Article
Language:	English
Published:	2022
Subjects:	Science::Chemistry Amides Arenes
Online Access:	https://hdl.handle.net/10356/154856
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	Nanyang Technological University
Language:	English

id	sg-ntu-dr.10356-154856
record_format	dspace
spelling	sg-ntu-dr.10356-1548562023-02-28T19:58:51Z Amide-directed C-H sodiation by a sodium hydride/iodide composite Huang, Yinhua Chan, Guo Hao Chiba, Shunsuke School of Physical and Mathematical Sciences Science::Chemistry Amides Arenes A new protocol for amide-directed ortho and lateral C-H sodiation is enabled by sodium hydride (NaH) in the presence of either sodium iodide (NaI) or lithium iodide (LiI). The transient organosodium intermediates could be transformed into functionalized aromatic compounds. Economic Development Board (EDB) Nanyang Technological University Accepted version Funding of S.C. for this work was provided by Nanyang Technological University, Singapore Economic Development Board (EDB), and Pfizer Asia Pacific Pte. Ltd. G.H.C. thanks to EDB-Industrial Post-graduate Program (IPP) for the scholarship support. 2022-01-17T01:18:47Z 2022-01-17T01:18:47Z 2017 Journal Article Huang, Y., Chan, G. H. & Chiba, S. (2017). Amide-directed C-H sodiation by a sodium hydride/iodide composite. Angewandte Chemie International Edition, 56(23), 6544-6547. https://dx.doi.org/10.1002/anie.201702512 1433-7851 https://hdl.handle.net/10356/154856 10.1002/anie.201702512 28449253 2-s2.0-85019623824 23 56 6544 6547 en EDB-IPP Angewandte Chemie International Edition This is the peer reviewed version of the following article: Huang, Y., Chan, G. H. & Chiba, S. (2017). Amide-directed C-H sodiation by a sodium hydride/iodide composite. Angewandte Chemie International Edition, 56(23), 6544-6547, which has been published in final form at https://doi.org/10.1002/anie.201702512. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. application/pdf
institution	Nanyang Technological University
building	NTU Library
continent	Asia
country	Singapore Singapore
content_provider	NTU Library
collection	DR-NTU
language	English
topic	Science::Chemistry Amides Arenes
spellingShingle	Science::Chemistry Amides Arenes Huang, Yinhua Chan, Guo Hao Chiba, Shunsuke Amide-directed C-H sodiation by a sodium hydride/iodide composite
description	A new protocol for amide-directed ortho and lateral C-H sodiation is enabled by sodium hydride (NaH) in the presence of either sodium iodide (NaI) or lithium iodide (LiI). The transient organosodium intermediates could be transformed into functionalized aromatic compounds.
author2	School of Physical and Mathematical Sciences
author_facet	School of Physical and Mathematical Sciences Huang, Yinhua Chan, Guo Hao Chiba, Shunsuke
format	Article
author	Huang, Yinhua Chan, Guo Hao Chiba, Shunsuke
author_sort	Huang, Yinhua
title	Amide-directed C-H sodiation by a sodium hydride/iodide composite
title_short	Amide-directed C-H sodiation by a sodium hydride/iodide composite
title_full	Amide-directed C-H sodiation by a sodium hydride/iodide composite
title_fullStr	Amide-directed C-H sodiation by a sodium hydride/iodide composite
title_full_unstemmed	Amide-directed C-H sodiation by a sodium hydride/iodide composite
title_sort	amide-directed c-h sodiation by a sodium hydride/iodide composite
publishDate	2022
url	https://hdl.handle.net/10356/154856
_version_	1759853989042585600

Amide-directed C-H sodiation by a sodium hydride/iodide composite

Similar Items