Amide-directed C-H sodiation by a sodium hydride/iodide composite
A new protocol for amide-directed ortho and lateral C-H sodiation is enabled by sodium hydride (NaH) in the presence of either sodium iodide (NaI) or lithium iodide (LiI). The transient organosodium intermediates could be transformed into functionalized aromatic compounds.
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Main Authors: | Huang, Yinhua, Chan, Guo Hao, Chiba, Shunsuke |
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Other Authors: | School of Physical and Mathematical Sciences |
Format: | Article |
Language: | English |
Published: |
2022
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/154856 |
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Institution: | Nanyang Technological University |
Language: | English |
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