Development of green and low-cost chiral oxidants for asymmetric catalytic hydroxylation of enals

Development of green and low-cost chiral oxidants for asymmetric catalytic hydroxylation of enals

A new type of chiral oxidants are developed and successfully applied in the asymmetric beta-hydroxylation of enals under the catalysis of an inexpensive achiral NHC catalyst. This type of chiral oxidants can be easily prepared from the low-cost starting materials of substituted benzoic acids and chi...

Full description

Saved in:
Bibliographic Details
Main Authors: Yang, Xiaoqun, Wang, Hongling, Jin, Zhichao, Chi, Robin Yonggui
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2022
Subjects:
Science::Chemistry
N-Heterocyclic Carbene
Organocatalysis
Online Access:https://hdl.handle.net/10356/155080
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English
id sg-ntu-dr.10356-155080
record_format dspace
spelling sg-ntu-dr.10356-1550802023-02-28T19:49:31Z Development of green and low-cost chiral oxidants for asymmetric catalytic hydroxylation of enals Yang, Xiaoqun Wang, Hongling Jin, Zhichao Chi, Robin Yonggui School of Physical and Mathematical Sciences Science::Chemistry N-Heterocyclic Carbene Organocatalysis A new type of chiral oxidants are developed and successfully applied in the asymmetric beta-hydroxylation of enals under the catalysis of an inexpensive achiral NHC catalyst. This type of chiral oxidants can be easily prepared from the low-cost starting materials of substituted benzoic acids and chiral prolinols through simple dehydrative amidation reactions Agency for Science, Technology and Research (A*STAR) Ministry of Education (MOE) National Research Foundation (NRF) Published version We acknowledge financial support from the National Natural Science Foundation of China (Nos. 21772029, 21801051, 21961006), The 10 Talent Plan (Shicengci) of Guizhou Province (No. [2016]5649), the Guizhou Province Returned Oversea Student Science and Technology Activity Program [No. (2014)-2], the Science and Technology Department of Guizhou Province (Nos. [2018]2802, [2019]1020, Qiankehejichu-ZK[2021]Key033), the Program of Introducing Talents of Discipline to Universities of China (111 Program, No. D20023) at Guizhou University, Frontiers Science Center for Asymmetric Synthesis and Medicinal Molecules, Department of Education, Guizhou Province [Qianjiaohe KY No. (2020)004], the Guizhou Province First-Class Disciplines Project [(Yiliu Xueke Jianshe Xiangmu)-GNYL(2017)008], Guizhou University of Traditional Chinese Medicine, and Guizhou University (China). Singapore National Research Foundation under its NRF Investigatorship (No. NRF-NRFI2016-06), the Ministry of Education, Singapore, under its MOE AcRF Tier 1 Award (Nos. RG108/16, RG5/19, RG1/18), MOE AcRF Tier 3 Award (No. MOE2018-T3-1-003), the Agency for Science, Technology and Research (A*STAR) under its A*STAR AME IRG Award (Nos. A1783c0008, A1783c0010), GSK-EDB Trust Fund, Nanyang Research Award Grant, Nanyang Technological University. 2022-02-08T02:31:29Z 2022-02-08T02:31:29Z 2021 Journal Article Yang, X., Wang, H., Jin, Z. & Chi, R. Y. (2021). Development of green and low-cost chiral oxidants for asymmetric catalytic hydroxylation of enals. Green Synthesis and Catalysis, 2(3), 295-298. https://dx.doi.org/10.1016/j.gresc.2021.05.002 2666-5549 https://hdl.handle.net/10356/155080 10.1016/j.gresc.2021.05.002 3 2 295 298 en NRF-NRFI2016-06 RG108/16 RG5/19 RG1/18 MOE2018-T3-1-003 A1783c0008 A1783c0010 Green Synthesis and Catalysis © 2021 Fudan University. Publishing Services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. This is an open access article under the CC BY NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Science::Chemistry
N-Heterocyclic Carbene
Organocatalysis
spellingShingle Science::Chemistry
N-Heterocyclic Carbene
Organocatalysis
Yang, Xiaoqun
Wang, Hongling
Jin, Zhichao
Chi, Robin Yonggui
Development of green and low-cost chiral oxidants for asymmetric catalytic hydroxylation of enals
description A new type of chiral oxidants are developed and successfully applied in the asymmetric beta-hydroxylation of enals under the catalysis of an inexpensive achiral NHC catalyst. This type of chiral oxidants can be easily prepared from the low-cost starting materials of substituted benzoic acids and chiral prolinols through simple dehydrative amidation reactions
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Yang, Xiaoqun
Wang, Hongling
Jin, Zhichao
Chi, Robin Yonggui
format Article
author Yang, Xiaoqun
Wang, Hongling
Jin, Zhichao
Chi, Robin Yonggui
author_sort Yang, Xiaoqun
title Development of green and low-cost chiral oxidants for asymmetric catalytic hydroxylation of enals
title_short Development of green and low-cost chiral oxidants for asymmetric catalytic hydroxylation of enals
title_full Development of green and low-cost chiral oxidants for asymmetric catalytic hydroxylation of enals
title_fullStr Development of green and low-cost chiral oxidants for asymmetric catalytic hydroxylation of enals
title_full_unstemmed Development of green and low-cost chiral oxidants for asymmetric catalytic hydroxylation of enals
title_sort development of green and low-cost chiral oxidants for asymmetric catalytic hydroxylation of enals
publishDate 2022
url https://hdl.handle.net/10356/155080
_version_ 1759857074547720192

Similar Items