Development of green and low-cost chiral oxidants for asymmetric catalytic hydroxylation of enals

• Main Authors: Yang, Xiaoqun, Wang, Hongling, Jin, Zhichao, Chi, Robin Yonggui
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Chemistry; N-Heterocyclic Carbene; Organocatalysis
• Online Access: https://hdl.handle.net/10356/155080
• Institution: Nanyang Technological University

A new type of chiral oxidants are developed and successfully applied in the asymmetric beta-hydroxylation of enals under the catalysis of an inexpensive achiral NHC catalyst. This type of chiral oxidants can be easily prepared from the low-cost starting materials of substituted benzoic acids and chi...