Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects

Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects

Nanoparticles that actively target tissues, with ligands attached at the extremity of polyethylene glycol (PEG) spacer, are a promising strategy to enhance target cell specificity and internalization. However, the interplay between the targeting ligands and the adjacent ligand-free PEG remains poorl...

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Bibliographic Details
Main Authors: Darwitan, Anastasia, Tan, Yang Fei, Wong, Yee Shan, Nedumaran, Anu Maashaa, Czarny, Bertrand, Venkatraman, Subbu
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2022
Subjects:
Science::Medicine
Engineering::Materials
Polyethylene Glycol
Liposome
Online Access:https://hdl.handle.net/10356/155234
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Institution: Nanyang Technological University
Language: English
Description
Summary:Nanoparticles that actively target tissues, with ligands attached at the extremity of polyethylene glycol (PEG) spacer, are a promising strategy to enhance target cell specificity and internalization. However, the interplay between the targeting ligands and the adjacent ligand-free PEG remains poorly understood.

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