Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects

Nanoparticles that actively target tissues, with ligands attached at the extremity of polyethylene glycol (PEG) spacer, are a promising strategy to enhance target cell specificity and internalization. However, the interplay between the targeting ligands and the adjacent ligand-free PEG remains poorl...

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Main Authors: Darwitan, Anastasia, Tan, Yang Fei, Wong, Yee Shan, Nedumaran, Anu Maashaa, Czarny, Bertrand, Venkatraman, Subbu
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/155234
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1552342022-03-01T07:56:25Z Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects Darwitan, Anastasia Tan, Yang Fei Wong, Yee Shan Nedumaran, Anu Maashaa Czarny, Bertrand Venkatraman, Subbu Lee Kong Chian School of Medicine (LKCMedicine) School of Materials Science and Engineering Science::Medicine Engineering::Materials Polyethylene Glycol Liposome Nanoparticles that actively target tissues, with ligands attached at the extremity of polyethylene glycol (PEG) spacer, are a promising strategy to enhance target cell specificity and internalization. However, the interplay between the targeting ligands and the adjacent ligand-free PEG remains poorly understood. Nanyang Technological University This study was supported by NTU – Northwestern Institute for Nanomedicine (project: nanotechnology to diagnose, prevent, and treat cardiovascular disease). 2022-03-01T07:56:25Z 2022-03-01T07:56:25Z 2020 Journal Article Darwitan, A., Tan, Y. F., Wong, Y. S., Nedumaran, A. M., Czarny, B. & Venkatraman, S. (2020). Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects. Expert Opinion On Drug Delivery, 17(8), 1165-1176. https://dx.doi.org/10.1080/17425247.2020.1777982 1742-5247 https://hdl.handle.net/10356/155234 10.1080/17425247.2020.1777982 32484723 2-s2.0-85087122889 8 17 1165 1176 en Expert Opinion on Drug Delivery © 2020 Informa UK Limited, trading as Taylor & Francis Group. All rights reserved.
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Science::Medicine
Engineering::Materials
Polyethylene Glycol
Liposome
spellingShingle Science::Medicine
Engineering::Materials
Polyethylene Glycol
Liposome
Darwitan, Anastasia
Tan, Yang Fei
Wong, Yee Shan
Nedumaran, Anu Maashaa
Czarny, Bertrand
Venkatraman, Subbu
Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects
description Nanoparticles that actively target tissues, with ligands attached at the extremity of polyethylene glycol (PEG) spacer, are a promising strategy to enhance target cell specificity and internalization. However, the interplay between the targeting ligands and the adjacent ligand-free PEG remains poorly understood.
author2 Lee Kong Chian School of Medicine (LKCMedicine)
author_facet Lee Kong Chian School of Medicine (LKCMedicine)
Darwitan, Anastasia
Tan, Yang Fei
Wong, Yee Shan
Nedumaran, Anu Maashaa
Czarny, Bertrand
Venkatraman, Subbu
format Article
author Darwitan, Anastasia
Tan, Yang Fei
Wong, Yee Shan
Nedumaran, Anu Maashaa
Czarny, Bertrand
Venkatraman, Subbu
author_sort Darwitan, Anastasia
title Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects
title_short Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects
title_full Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects
title_fullStr Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects
title_full_unstemmed Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects
title_sort targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects
publishDate 2022
url https://hdl.handle.net/10356/155234
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