Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects
Nanoparticles that actively target tissues, with ligands attached at the extremity of polyethylene glycol (PEG) spacer, are a promising strategy to enhance target cell specificity and internalization. However, the interplay between the targeting ligands and the adjacent ligand-free PEG remains poorl...
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sg-ntu-dr.10356-1552342022-03-01T07:56:25Z Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects Darwitan, Anastasia Tan, Yang Fei Wong, Yee Shan Nedumaran, Anu Maashaa Czarny, Bertrand Venkatraman, Subbu Lee Kong Chian School of Medicine (LKCMedicine) School of Materials Science and Engineering Science::Medicine Engineering::Materials Polyethylene Glycol Liposome Nanoparticles that actively target tissues, with ligands attached at the extremity of polyethylene glycol (PEG) spacer, are a promising strategy to enhance target cell specificity and internalization. However, the interplay between the targeting ligands and the adjacent ligand-free PEG remains poorly understood. Nanyang Technological University This study was supported by NTU – Northwestern Institute for Nanomedicine (project: nanotechnology to diagnose, prevent, and treat cardiovascular disease). 2022-03-01T07:56:25Z 2022-03-01T07:56:25Z 2020 Journal Article Darwitan, A., Tan, Y. F., Wong, Y. S., Nedumaran, A. M., Czarny, B. & Venkatraman, S. (2020). Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects. Expert Opinion On Drug Delivery, 17(8), 1165-1176. https://dx.doi.org/10.1080/17425247.2020.1777982 1742-5247 https://hdl.handle.net/10356/155234 10.1080/17425247.2020.1777982 32484723 2-s2.0-85087122889 8 17 1165 1176 en Expert Opinion on Drug Delivery © 2020 Informa UK Limited, trading as Taylor & Francis Group. All rights reserved. |
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Science::Medicine Engineering::Materials Polyethylene Glycol Liposome Darwitan, Anastasia Tan, Yang Fei Wong, Yee Shan Nedumaran, Anu Maashaa Czarny, Bertrand Venkatraman, Subbu Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects |
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Nanoparticles that actively target tissues, with ligands attached at the extremity of polyethylene glycol (PEG) spacer, are a promising strategy to enhance target cell specificity and internalization. However, the interplay between the targeting ligands and the adjacent ligand-free PEG remains poorly understood. |
author2 |
Lee Kong Chian School of Medicine (LKCMedicine) |
author_facet |
Lee Kong Chian School of Medicine (LKCMedicine) Darwitan, Anastasia Tan, Yang Fei Wong, Yee Shan Nedumaran, Anu Maashaa Czarny, Bertrand Venkatraman, Subbu |
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Article |
author |
Darwitan, Anastasia Tan, Yang Fei Wong, Yee Shan Nedumaran, Anu Maashaa Czarny, Bertrand Venkatraman, Subbu |
author_sort |
Darwitan, Anastasia |
title |
Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects |
title_short |
Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects |
title_full |
Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects |
title_fullStr |
Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects |
title_full_unstemmed |
Targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects |
title_sort |
targeting efficiency of nanoliposomes on atherosclerotic foam cells : polyethylene glycol-to-ligand ratio effects |
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2022 |
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https://hdl.handle.net/10356/155234 |
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1726885514120790016 |