Regio-and stereoselective C(sp<sup>2</sup>)-H acylation of enamides with aldehydes : via transition-metal-free photoredox catalysis
A straightforward and efficient C(sp2)-H acylation of enamides with aldehydes via transition-metal-free photoredox catalysis is demonstrated. The transformation proceeded smoothly without resorting to expensive and potentially toxic iridium or ruthenium polypyridyl-based photocatalysts under mild co...
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sg-ntu-dr.10356-1556112022-03-16T06:30:18Z Regio-and stereoselective C(sp<sup>2</sup>)-H acylation of enamides with aldehydes : via transition-metal-free photoredox catalysis Zhao, Kai Zhang, Xiao-Chen Tao, Ji-Yu Wu, Xian-Dan Wu, Jia-Xu Li, Wei-Ming Zhu, Tong-Hao Loh, Teck-Peng School of Physical and Mathematical Sciences Science::Chemistry Enamides Catalysis A straightforward and efficient C(sp2)-H acylation of enamides with aldehydes via transition-metal-free photoredox catalysis is demonstrated. The transformation proceeded smoothly without resorting to expensive and potentially toxic iridium or ruthenium polypyridyl-based photocatalysts under mild conditions, furnishing a diverse range of synthetically crucial, geometrically defined β-acylated enamides in a stereoselective and regioselective manner. This journal is We gratefully acknowledge the financial support from the National Natural Science Foundation of China (21801129), the Natural Science Research Projects in Jiangsu Higher Education Institutions (18KJB150018), the National Students’ Platform for Innovation and Entrepreneurship Training Program (201910291012Z) and Nanjing Tech University (Start-up Grant No. 39837137, 39837101 and 3827401739). 2022-03-16T06:30:18Z 2022-03-16T06:30:18Z 2020 Journal Article Zhao, K., Zhang, X., Tao, J., Wu, X., Wu, J., Li, W., Zhu, T. & Loh, T. (2020). Regio-and stereoselective C(sp<sup>2</sup>)-H acylation of enamides with aldehydes : via transition-metal-free photoredox catalysis. Green Chemistry, 22(16), 5497-5503. https://dx.doi.org/10.1039/d0gc01947j 1463-9262 https://hdl.handle.net/10356/155611 10.1039/d0gc01947j 2-s2.0-85090767308 16 22 5497 5503 en Green Chemistry © 2020 The Royal Society of Chemistry. All rights reserved. |
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Science::Chemistry Enamides Catalysis Zhao, Kai Zhang, Xiao-Chen Tao, Ji-Yu Wu, Xian-Dan Wu, Jia-Xu Li, Wei-Ming Zhu, Tong-Hao Loh, Teck-Peng Regio-and stereoselective C(sp<sup>2</sup>)-H acylation of enamides with aldehydes : via transition-metal-free photoredox catalysis |
| description |
A straightforward and efficient C(sp2)-H acylation of enamides with aldehydes via transition-metal-free photoredox catalysis is demonstrated. The transformation proceeded smoothly without resorting to expensive and potentially toxic iridium or ruthenium polypyridyl-based photocatalysts under mild conditions, furnishing a diverse range of synthetically crucial, geometrically defined β-acylated enamides in a stereoselective and regioselective manner. This journal is |
| author2 |
School of Physical and Mathematical Sciences |
| author_facet |
School of Physical and Mathematical Sciences Zhao, Kai Zhang, Xiao-Chen Tao, Ji-Yu Wu, Xian-Dan Wu, Jia-Xu Li, Wei-Ming Zhu, Tong-Hao Loh, Teck-Peng |
| format |
Article |
| author |
Zhao, Kai Zhang, Xiao-Chen Tao, Ji-Yu Wu, Xian-Dan Wu, Jia-Xu Li, Wei-Ming Zhu, Tong-Hao Loh, Teck-Peng |
| author_sort |
Zhao, Kai |
| title |
Regio-and stereoselective C(sp<sup>2</sup>)-H acylation of enamides with aldehydes : via transition-metal-free photoredox catalysis |
| title_short |
Regio-and stereoselective C(sp<sup>2</sup>)-H acylation of enamides with aldehydes : via transition-metal-free photoredox catalysis |
| title_full |
Regio-and stereoselective C(sp<sup>2</sup>)-H acylation of enamides with aldehydes : via transition-metal-free photoredox catalysis |
| title_fullStr |
Regio-and stereoselective C(sp<sup>2</sup>)-H acylation of enamides with aldehydes : via transition-metal-free photoredox catalysis |
| title_full_unstemmed |
Regio-and stereoselective C(sp<sup>2</sup>)-H acylation of enamides with aldehydes : via transition-metal-free photoredox catalysis |
| title_sort |
regio-and stereoselective c(sp<sup>2</sup>)-h acylation of enamides with aldehydes : via transition-metal-free photoredox catalysis |
| publishDate |
2022 |
| url |
https://hdl.handle.net/10356/155611 |
| _version_ |
1728433365242085376 |