Sensitivity of mycobacterium leprae to telacebec

Sensitivity of mycobacterium leprae to telacebec

The treatment of leprosy is long and complex, benefiting from the development of sterilizing, rapidly-acting drugs. Reductive evolution made Mycobacterium leprae exquisitely sensitive to Telacebec, a phase 2 drug candidate for tuberculosis. The unprecedented potency of Telacebec against M. leprae wa...

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Bibliographic Details
Main Authors: Lahiri, Ramanuj, Adams, Linda B., Thomas, Sangeeta Susan, Pethe, Kevin
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2022
Subjects:
Science::Medicine
Leprosy
Telacebec
Online Access:https://hdl.handle.net/10356/160139
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Institution: Nanyang Technological University
Language: English
Description
Summary:The treatment of leprosy is long and complex, benefiting from the development of sterilizing, rapidly-acting drugs. Reductive evolution made Mycobacterium leprae exquisitely sensitive to Telacebec, a phase 2 drug candidate for tuberculosis. The unprecedented potency of Telacebec against M. leprae warrants further validation in clinical trials.

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