Macrolactam synthesis via ring-closing alkene-alkene cross-coupling reactions

Reported herein is a practical method for macrolactam synthesis via a Rh(III)-catalyzed ring closing alkene-alkene cross-coupling reaction. The reaction proceeded via a Rh-catalyzed alkenyl sp2 C-H activation process, which allows access to macrocyclic molecules of different ring sizes. Macrolactams...

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Bibliographic Details
Main Authors: Maraswami, Manikantha, Goh, Jeffrey, Loh, Teck-Peng
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10356/160363
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Institution: Nanyang Technological University
Language: English