Scar prevention through topical delivery of gelatin-tyramine-siSPARC nanoplex loaded in dissolvable hyaluronic acid microneedle patch across skin barrier
Currently, there is no effective method to prevent the formation of hypertrophic scars and keloids, which can cause severe physical and psychological burdens to patients. Secreted protein acidic and cysteine-rich (SPARC) is involved in wound fibrosis by modulating fibroblast functions, causing exces...
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Main Authors: | Chun, Yong Yao, Tan, William Wei Ren, Vos, Marcus Ivan Gerard, Chan, Wen Kiat, Tey, Hong Liang, Tan, Nguan Soon, Tan, Timothy Thatt Yang |
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Other Authors: | School of Chemical and Biomedical Engineering |
Format: | Article |
Language: | English |
Published: |
2022
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/162361 |
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Institution: | Nanyang Technological University |
Language: | English |
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