Viral dynamics and immune correlates of coronavirus disease 2019 (COVID-19) severity

• Main Authors: Young, Barnaby Edward, Ong, Sean W. X., Ng, Lisa F. P., Anderson, Danielle E., Chia, Wan Ni, Chia, Po Ying, Ang, Li Wei, Mak, Tze-Minn, Kalimuddin, Shirin, Chai, Louis Yi Ann, Pada, Surinder, Tan, Seow Yen, Sun, Louisa, Parthasarathy, Purnima, Fong, Siew-Wai, Chan, Yi-Hao, Tan, Chee Wah, Lee, Bernett, Rötzschke, Olaf, Ding, Ying, Tambyah, Paul, Low, Jenny G. H., Cui, Lin, Barkham, Timothy, Lin, Raymond Tzer Pin, Leo, Yee Sin, Renia, Laurent, Wang, Lin-Fa, Lye, David Chien
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2022
• Subjects: Science::Medicine; COVID-19; Cytokines
• Online Access: https://hdl.handle.net/10356/162756
• Institution: Nanyang Technological University

Background. Key knowledge gaps remain in the understanding of viral dynamics and immune response of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection. Methods. We evaluated these characteristics and established their association with clinical severity in a prospective observatio...