Structure activity relationship of pyrazinoic acid analogs as potential antimycobacterial agents
Tuberculosis (TB) remains a leading cause of infectious disease-related mortality and morbidity. Pyrazinamide (PZA) is a critical component of the first-line TB treatment regimen because of its sterilizing activity against non-replicating Mycobacterium tuberculosis (Mtb), but its mechanism of action...
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Main Authors: | , , , , , , , , , |
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格式: | Article |
語言: | English |
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2023
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在線閱讀: | https://hdl.handle.net/10356/164677 |
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