Automatic DNA replication tract measurement to assess replication and repair dynamics at the single-molecule level

• Main Authors: Li, Longjie, Kolinjivadi, Arun Mouli, Ong, Kok Haur, Young, David M., Marini, Gabriel Pik Liang, Chan, Sock Hoai, Chong, Siao Ting, Chew, Ee Ling, Lu, Haoda, Gole, Laurent, Yu, Weimiao, Ngeow, Joanne
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Medicine; Sofware; Replication
• Online Access: https://hdl.handle.net/10356/164980
• Institution: Nanyang Technological University

DNA fibre assay has a potential application in genomic medicine, cancer and stem cell research at the single-molecule level. A major challenge for the clinical and research implementation of DNA fibre assays is the slow speed in which manual analysis takes place as it limits the clinical actionabili...