Discovery of super-insecticide-resistant dengue mosquitoes in Asia: threats of concomitant knockdown resistance mutations

• Main Authors: Kasai, Shinji, Itokawa, Kentaro, Uemura, Nozomi, Takaoka, Aki, Furutani, Shogo, Maekawa, Yoshihide, Kobayashi, Daisuke, Imanishi-Kobayashi, Nozomi, Amoa-Bosompem, Michael, Murota, Katsunori, Higa, Yukiko, Kawada, Hitoshi, Minakawa, Noboru, Cuong, Tran Chi, Yen, Nguyen Thi, Phong, Tran Vu, Keo, Sath, Kang, Kroesna, Miura, Kozue, Ng, Lee Ching, Teng, Hwa-Jen, Dadzie, Samuel, Subekti, Sri, Mulyatno, Kris Cahyo, Sawabe, Kyoko, Tomita, Takashi, Komagata, Osamu
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Biological sciences; Infectious Disease; Mosquito Vectors
• Online Access: https://hdl.handle.net/10356/169836
• Institution: Nanyang Technological University

Aedes aegypti (Linnaeus, 1762) is the main mosquito vector for dengue and other arboviral infectious diseases. Control of this important vector highly relies on the use of insecticides, especially pyrethroids. The high frequency (>78%) of the L982W substitution was detected at the target site of...