NHC-catalyzed [12+2] reaction of polycyclic arylaldehydes for access to indole derivatives

NHC-catalyzed [12+2] reaction of polycyclic arylaldehydes for access to indole derivatives

An N-heterocyclic carbene (NHC) catalyzed enantio- and diastereoselective [12+2] cycloaddition is disclosed to rapidly construct sophisticated molecules bearing a tricyclic core and morpholine moiety. The success of our reaction relies on the NHC-catalyzed remote sp3 (C-H) bond activation of a 5H-be...

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Bibliographic Details
Main Authors: Ji, Hong, Zou, Juan, Mou, Chengli, Liu, Yonggui, Ren, Shi-Chao, Chi, Robin Yonggui
Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
Format: Article
Language:English
Published: 2023
Subjects:
Engineering::Bioengineering
Aldehyde
Bismerthiazol
Online Access:https://hdl.handle.net/10356/170281
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/170281

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