Macrophage membrane-coated nanoparticles sensitize glioblastoma to radiation by suppressing proneural–mesenchymal transformation in glioma stem cells

• Main Authors: Li, Ruiqi, Chen, Lian, Ji, Qin, Liang, Qing, Zhu, Ying, Fu, Wei, Chen, Tianyou, Duan, Hongwei, He, Wenshan, Xu, Zushun, Dai, Xiaofang, Ren, Jinghua
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2023
• Subjects: Engineering::Chemical engineering; Glioblastoma; Glioma Stem Cells
• Online Access: https://hdl.handle.net/10356/170643
• Institution: Nanyang Technological University

Radiotherapy is identified as a crucial treatment for patients with glioblastoma, but recurrence is inevitable. The efficacy of radiotherapy is severely hampered partially due to the tumor evolution. Growing evidence suggests that proneural glioma stem cells can acquire mesenchymal features coupled...