Development of bioinformatics methods and platforms to characterize chromatin interactions

Chromatin interactions are loops between genomic elements, such as enhancers and promoters, that regulate gene transcription. High throughput chromosome conformation capture (Hi-C) is an important method for studying chromatin interactions in the whole genome. Our aim is to understand or address the...

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Bibliographic Details
Main Author: Chen, Kaijing
Other Authors: Melissa Jane Fullwood
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2024
Subjects:
Online Access:https://hdl.handle.net/10356/177337
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Institution: Nanyang Technological University
Language: English