Development of bioinformatics methods and platforms to characterize chromatin interactions
Chromatin interactions are loops between genomic elements, such as enhancers and promoters, that regulate gene transcription. High throughput chromosome conformation capture (Hi-C) is an important method for studying chromatin interactions in the whole genome. Our aim is to understand or address the...
محفوظ في:
المؤلف الرئيسي: | Chen, Kaijing |
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مؤلفون آخرون: | Melissa Jane Fullwood |
التنسيق: | Thesis-Doctor of Philosophy |
اللغة: | English |
منشور في: |
Nanyang Technological University
2024
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الموضوعات: | |
الوصول للمادة أونلاين: | https://hdl.handle.net/10356/177337 |
الوسوم: |
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مواد مشابهة
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منشور في: (2020) -
Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth
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منشور في: (2024) -
Long-distance repression by human silencers: chromatin interactions and phase separation in silencers
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منشور في: (2022) -
Chromatin interactions and regulatory elements in cancer : from bench to bedside
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منشور في: (2020)