Functional role of HMGA2 in DNA repair and genome stability of HeLa cells.

• Main Author: Kok, Chun Peng.
• Other Authors: Peter Droge
• Format: Final Year Project
• Language: English
• Published: 2009
• Subjects: DRNTU::Science::Biological sciences::Genetics
• Online Access: http://hdl.handle.net/10356/18727
• Institution: Nanyang Technological University

High Mobility Group AT-hooks (HMGA) proteins are non-histone chromosomal proteins that are involved in numerous nuclear activities such as chromatin dynamics maintenance and indirect regulation of gene transcription. Until today, the involvement of HMGA2 proteins in DNA repair is still under investi...