Carbonylation is a hallmark of oxidative stress induced by lipid peroxidation products, 4-hydroxy-2-nonenal and 4-hydroxy-2- hexenal, on insulin signalling in L6 myoblasts.

Peripheral insulin resistance is one of the defining characteristics of type 2 diabetes - a metabolic disorder commonly associated with oxidative stress. Obesity and exposure to atmospheric oxidants, such as ozone gas, induces oxidative stress which increases lipid peroxidation. However, it is still...

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Bibliographic Details
Main Author: Chionh, Yok Hian.
Other Authors: School of Biological Sciences
Format: Final Year Project
Language:English
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/10356/18971
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Institution: Nanyang Technological University
Language: English