Carbonylation is a hallmark of oxidative stress induced by lipid peroxidation products, 4-hydroxy-2-nonenal and 4-hydroxy-2- hexenal, on insulin signalling in L6 myoblasts.
Peripheral insulin resistance is one of the defining characteristics of type 2 diabetes - a metabolic disorder commonly associated with oxidative stress. Obesity and exposure to atmospheric oxidants, such as ozone gas, induces oxidative stress which increases lipid peroxidation. However, it is still...
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| 格式: | Final Year Project |
| 語言: | English |
| 出版: |
2009
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| 在線閱讀: | http://hdl.handle.net/10356/18971 |
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| 機構: | Nanyang Technological University |
| 語言: | English |