Silver catalyzed multicomponent synthesis of aminoindolizines

Silver catalyzed multicomponent synthesis of aminoindolizines

A direct and efficient approach to 1-aminoindolizines through three component one pot reaction of heteroaryl aldehydes, second amines, and alkynes catalyzed by AgBF4 has been developed. This methodology provides rapid access to construct a diversified oriented library of indolizines.

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Bibliographic Details
Main Author: Bai, Yaguang
Other Authors: Liu Xuewei
Format: Final Year Project
Language:English
Published: 2010
Subjects:
DRNTU::Science::Chemistry::Organic chemistry::Heterocyclic compounds
Online Access:http://hdl.handle.net/10356/20852
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Institution: Nanyang Technological University
Language: English
Description
Summary:A direct and efficient approach to 1-aminoindolizines through three component one pot reaction of heteroaryl aldehydes, second amines, and alkynes catalyzed by AgBF4 has been developed. This methodology provides rapid access to construct a diversified oriented library of indolizines.

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