Iron-catalyzed amidation of 1,3-dicarbonyl compounds.

• 主要作者: Ong, Wei Ting.
• 其他作者: Philip Wai Hong Chan
• 格式: Final Year Project
• 語言: English
• 出版: 2010
• 主題: DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis
• 在線閱讀: http://hdl.handle.net/10356/39882
• 機構: Nanyang Technological University

An efficient Fe-catalyzed amidation of 1,3-dicarbonyl compounds to α-amidated products through C(sp3)-H functionalization is achieved via 2 methods; indirect method of using PhI=NTs (Ts = toluene-4-sulfonyl) as nitrogen source and direct method of using PhI(OAc)2 as oxidant and TsNH2 as nitrogen sou...