Modulation of thelper polarization by GM-CSF and the dectin-1 ligand, curdlan.

• Main Author: Loy, Yawen.
• Other Authors: Ruedl Christiane
• Format: Final Year Project
• Language: English
• Published: 2011
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Immunology
• Online Access: http://hdl.handle.net/10356/45268
• Institution: Nanyang Technological University

Dendritic cells (DCs) work as antigen presenting cells that help in the polarization of CD4 T cells into effector and regulatory subsets. Pathogen recognition receptors (PRRs) like Toll-like receptors (TLRs) and C-type lectin receptors (CLRs) on DCs recognise pathogen-associated molecular patterns (...