Characterization of SMAD3 function in skeletal muscle growth

• المؤلف الرئيسي: Ge, Xiaojia
• مؤلفون آخرون: Ravi Kambadur
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2012
• الموضوعات: DRNTU::Science::Biological sciences::Molecular biology; DRNTU::Science::Biological sciences::Genetics
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/48683
• المؤسسة: Nanyang Technological University

Smad3 is a key intracellular signaling mediator for Myostatin and TGF-β1, two TGF-β superfamily members and are key regulators of skeletal muscle growth and homeostasis. Despite extensive studies about the functions and signaling of Myostatin/TGF-β1, little is known about the regulatory role of Smad...