Characterization of SMAD3 function in skeletal muscle growth

• Main Author: Ge, Xiaojia
• Other Authors: Ravi Kambadur
• Format: Theses and Dissertations
• Language: English
• Published: 2012
• Subjects: DRNTU::Science::Biological sciences::Molecular biology; DRNTU::Science::Biological sciences::Genetics
• Online Access: https://hdl.handle.net/10356/48683
• Institution: Nanyang Technological University

Smad3 is a key intracellular signaling mediator for Myostatin and TGF-β1, two TGF-β superfamily members and are key regulators of skeletal muscle growth and homeostasis. Despite extensive studies about the functions and signaling of Myostatin/TGF-β1, little is known about the regulatory role of Smad...