Role of autophagy in regulation of genome stability.

• 主要作者: Ng, Yan Ting.
• 其他作者: Wong, Esther Siew Peng
• 格式: Final Year Project
• 語言: English
• 出版: 2013
• 主題: DRNTU::Science::Biological sciences::Molecular biology
• 在線閱讀: http://hdl.handle.net/10356/52725

Genomic instability is a fundamental component of cancer and aging. Defects in autophagy, a lysosome-mediated degradation pathway, have recently been associated with genomic instability but the exact mechanisms underlying this association remain ill-defined. Here, we have identified a role of autoph...