Role of autophagy in regulation of genome stability.

• Main Author: Ng, Yan Ting.
• Other Authors: Wong, Esther Siew Peng
• Format: Final Year Project
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/52725
• Institution: Nanyang Technological University

Genomic instability is a fundamental component of cancer and aging. Defects in autophagy, a lysosome-mediated degradation pathway, have recently been associated with genomic instability but the exact mechanisms underlying this association remain ill-defined. Here, we have identified a role of autoph...