Role of autophagy in regulation of genome stability.

• المؤلف الرئيسي: Ng, Yan Ting.
• مؤلفون آخرون: Wong, Esther Siew Peng
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2013
• الموضوعات: DRNTU::Science::Biological sciences::Molecular biology
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/52725

Genomic instability is a fundamental component of cancer and aging. Defects in autophagy, a lysosome-mediated degradation pathway, have recently been associated with genomic instability but the exact mechanisms underlying this association remain ill-defined. Here, we have identified a role of autoph...