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A study of the functional domains of the type I iterative polyketide synthase CalE8 in calicheamicin biosynthesis.

Naturally occurring enediynes are potent antibiotics produced by soil and marine microorganisms. Their robust antitumor activities and unique mode of action make them a significant topic of study. The synthesis of the enediyne products is initiated by a type I iterative polyketide synthase (PKS). In...

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書目詳細資料
主要作者: Elavazhagan Murugan.
其他作者: Liang Zhao-Xun
格式: Theses and Dissertations
語言:English
出版: 2013
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在線閱讀:https://hdl.handle.net/10356/53489
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