Native chemical ligation on aspartic acid and its application towards convergent synthesis of homogeneous N-glycoprotein

Total synthesis of native and functional proteins was almost unachievable back in the early 1990s, but thanks to Prof Kent’s development on native chemical ligation (NCL), chemical protein synthesis has become attainable. The basis of NCL technique is the chemoselective reaction between a peptide th...

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Bibliographic Details
Main Author: Chai, Hua
Other Authors: Liu Chuan Fa
Format: Theses and Dissertations
Language:English
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/10356/66214
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Institution: Nanyang Technological University
Language: English